Human emotions study through biomarkers is a recent field with high importance to all modern society. Imbalanced parameters to external stimuli induce stress both physical as psychological that has been related to several diseases and discordant social behavior. This is particular important for the military, in order to control the risk of their missions and avoid undesirable post-operations psychological disorders. In this project, civilian, military and business' association researchers (from FCT-NOVA, CINAMIL/Academia Militar and CITEVE) are united with the common goal to study and early detect stress biomarkers, through non-invasive methodologies (using sweat as target biological fluid), and able to operate in field with real-time monitoring and integrated in wearables. The project STRESSENSE has a multidisciplinary, experienced team, with extensive expertise in electrochemistry, biochemistry, biomolecules detection, materials and data-processing, together with knowledge associated to individuals' emotional and physical behavior. The military forces' volunteers will take part of a case-of-study that will allow making the proof-of-concept of the new proposed medical methodology. This will be based in low-cost materials where molecular recognition elements will be incorporated. The fingerprint data obtained from the samples electrochemical analysis will be correlated with results from classical bioanalytical techniques, clinical medicine routine analysis, and the volunteers' social behavior and routines, allowing attaining a pattern related to stress' risks. The sensors will then be integrated in fabrics aiming to attain wireless (or via military channels) communication wearables. The new biotechnology sensing devices to be developed have high interest to medicine and health care services, allowing the remote, continuous monitoring to stress related parameters and its correlation to the global individual health conditions (physical and psychological). This is a project where cooperative work between civilian (academic and industry) and military researchers will conduct to a high gain investigation with expected useful outcomes for society (both civil and military) and industry (innovative commercial sensing devices).